Oncohematology
Flaming Plasma Cells in Bone Marrow: A Clinical Case
A clinical case of flaming plasma cells in bone marrow with severe anemia and no monoclonal M-gradient, presenting a diagnostic challenge.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Emperipolesis in Megakaryocytes: Bone Marrow Cytology
The phenomenon of emperipolesis in bone marrow: active penetration of intact cells into the megakaryocyte cytoplasm in a puncture smear.
Hematology
Bone Marrow Cytology in Hepatosplenomegaly: A Case
Clinical case: An 8-year-old boy with hepatosplenomegaly and pancytopenia. Bone marrow aspirate shows altered macrophages. Determine the diagnosis.
Hematology
Exercise: Find the Leukocyte Among Normoblasts in Cell Gallery
Clinical digital microscopy exercise: identify the misclassified leukocyte in a gallery of normoblasts (NRBCs) in hemolytic disease of the newborn.
Lab test interpretation
Urine Amylase Determination by Caraway Method in Pancreatitis
Examples of sharp increases in urine diastase and blood amylase post-holidays. Features of 1:10 and 1:100 urine dilution in the amyloclastic analysis method.
Oncohematology
Bone Marrow in Chronic Lymphocytic Leukemia Remission
Morphological features of bone marrow aspirate in chronic lymphocytic leukemia remission: 5% lymphoid cells, active erythroid proliferation.
Lab test interpretation
Cervical Columnar Epithelium in a Vaginal Smear
Morphology of endocervical columnar epithelium in a gynecological smear: microscopic appearance, cell sheets, and differential diagnosis.
Oncohematology
Hematology Exercise: Blast Classification in Blood Smear
Practical morphology task: identify the type of blast cells in a peripheral blood smear and write your classification in the comments.
Oncohematology
Bone Marrow Cytology in Multiple Myeloma
Morphology of atypical plasma cells in bone marrow aspirate in multiple myeloma. Clinical case of a patient with myeloma nephropathy.
Hematology
Osteoblast Morphology in Bone Marrow Smears
Cytological features of osteoblasts in bone marrow aspirates: morphology of large cells with eccentric nuclei and differentiation from plasma cells.
Hematology
Severe Iron Deficiency Anemia: Blood Counts and Smear
A clinical case of severe iron deficiency anemia: interpretation of red blood cell indices, iron metabolism, and erythrocyte morphology in a blood smear.
Lab test interpretation
Fungal Mycelium in Native Sputum Smear Microscopy
Microscopic examination of native sputum smear: branching fungal mycelium detected amidst erythrocytes at 100x and 400x magnification. A case study.