Hematology
Body's Adaptation to Severe Anemia: Mechanisms
Why patients with chronic severe anemia and hemoglobin of 70 g/L can tolerate physical activity: mechanisms of hypoxia compensation and adaptation.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Laboratory methods
Optical Platelet Count (PLT-O) on Hematology Analyzer
Understanding the principle of optical fluorescent platelet counting (PLT-O) in the RET channel of a hematology analyzer, scattergram interpretation, and IPF fraction.
Oncohematology
Acute Promyelocytic Leukemia: Cell Morphology in Smear
A clinical case of acute promyelocytic leukemia: 89% atypical promyelocytes, hemorrhagic syndrome, anemia, and severe thrombocytopenia in a blood smear.
Hematology
Hematology Case: Identifying Cells in a Blood Smear
A diagnostic challenge in blood smear microscopy for a 41-year-old woman. Evaluate leukocyte morphology, analyzer data, and the DIFF scattergram.
Lab test interpretation
Ascitic Fluid Cytology: Atypical Cells Morphology
Morphology of atypical cells in ascitic fluid: microscopy of native preparations and Romanowsky staining when malignancy is suspected.
Hematology
Morphology of Segmented Neutrophils in Blood Smear
Explore the morphological features of segmented neutrophils in peripheral blood smears: nuclear segmentation, cytoplasmic granularity, and microscopy.
Oncohematology
Differential Diagnosis of Blasts in Blood Smears: Common Errors
Analysis of typical errors in blood smear microscopy: why blast cells are mistaken for reactive lymphocytes and how to suspect acute leukemia in time.
Oncohematology
Cellular Cannibalism: Entosis in Cytological Diagnosis
What are cellular cannibalism and entosis in malignant tumors: biological mechanisms, cytological signs, and clinical significance of the phenomenon.
Lab test interpretation
Alkaline Phosphatase in Liver Injury: An Assessment Algorithm
Causes of elevated alkaline phosphatase in hepatitis, cholestasis, and liver tumors. Differential diagnosis algorithm based on enzyme elevation levels.
Oncohematology
Morphological Signs of Myelodysplasia in Bone Marrow
Bone marrow morphology in suspected MDS: signs of hematopoietic dysplasia, uninuclear megakaryocytes, and pathological erythrocyte mitoses.
Hematology
Hematology Case: Granulocytes with Inclusions in Smear
Laboratory hematology test: identify the type of granulocytes with dermatan sulfate inclusions in a peripheral blood smear using a photomicrograph.
Hematology
Endothelial Cells in Peripheral Blood Smear
How to distinguish endothelial cells from hairy lymphocytes in a blood smear: causes of endothelial contamination during venipuncture and their morphological features.