
Cell Morphology: A Diagnostic Microscopy Challenge
A cell morphology challenge: identify the origin of cells with cytoplasmic projections forming clusters in a microscopic preparation.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

A cell morphology challenge: identify the origin of cells with cytoplasmic projections forming clusters in a microscopic preparation.

A 90-year-old female patient's complete blood count: leukocytosis 22.7×10⁹/L, thrombocytopenia, severe anemia, and 48% blast cells in the peripheral blood smear.

A diagnostic challenge in liquid-based cytology: microscopic findings of a gynecological ThinPrep smear from a 32-year-old patient. Identify the pathology.

A diagnostic challenge in stool microscopy for an HIV-positive patient: identify a parasitic object 25–30 µm in size using three microscopy methods.

A clinical case of Cryptococcus neoformans detection when cutaneous leishmaniasis was suspected. Morphology of yeast-like cells in a cytological smear from a wound.

An interactive blood cell morphology challenge: test your knowledge and identify the specific name of the blast depicted in the diagram.

A diagnostic challenge in stool microscopy using the Kato method: identify the parasite species based on egg morphology found during laboratory examination.

Microscopic view of vaginal candidiasis: detection of spores and pseudomycelium of Candida yeast-like fungi in a smear stained by Romanowsky method.

Morphological picture of bone marrow aspirate in acute leukemia relapse: blast cells 9.6% and marked erythroid hyperplasia up to 58.2%.

Oncohematology test case: changes in which membrane protein can be observed in blasts and contribute to their intercellular adhesion.

Morphology and counting of schistocytes in blood smears in microangiopathic hemolytic anemia. Evaluation of fragmented red blood cells (FRC) on Sysmex analyzers.

Morphological features of trematodes: Clonorchis sinensis, Opisthorchis viverrini, Fasciola hepatica, and Paragonimus westermani in parasitology.