Oncohematology

Myelodysplasia and Dysgranulopoiesis Signs in Blood Smear

Blood smear analysis of a patient with anemia and leukopenia: dysgranulopoiesis, toxic granulation, Döhle bodies, and giant platelets in dysplasia.

🔬 Blood smear - external quality control from 🇮🇱 Israel.

Patient, 67 years old. Hemoglobin — 87 g/L, leukocytes — 3.0 × 10⁹/L. We observe a left shift up to single promyelocytes, dysgranulation, vacuolization and toxic granulation of the cytoplasm, Döhle bodies. Single erythroblasts, acanthocytes.

❓What do the arrows indicate?

🙏The publication was kindly provided by the Head of the Morphology/IFT Department of the Ha-Emek Medical Center Laboratory in Afula, Israel - Anna Belen.