Adult-onset hyposegmentation (Pseudopelgerization)
✅ Blood smear of a 1-year-old girl, observed in the hematology department with a diagnosis of “anemia of unknown origin”. Such changes were not noted in previous blood smears.
✅ Currently, pseudopelgerization of neutrophils is considered the earliest predictor of myelodysplastic conditions. It is assumed that Pelgeroid cells may appear in peripheral blood long before the manifestation of hemoblastoses and MDS.
Romanowsky-Giemsa stain, magnification x1000.
🙏 The images were kindly provided by clinical laboratory diagnostics intern Nadezhda Petrenko, Blagoveshchensk.
