Laboratory methods

Purified DNA Solution: Causes of High Viscosity

Why purified genomic DNA solutions are highly viscous: physicochemical properties of eukaryotic DNA molecules in the clinical laboratory.

Macrophoto of a viscous, stringy solution of purified genomic DNA in a test tube
Macrophoto of a viscous, stringy solution of purified genomic DNA in a test tube

🧪Photograph of a viscous solution of purified DNA🧬 The length of a fully extended eukaryotic DNA molecule of the entire genome is about 3 meters! This is why DNA forms such a viscous solution. Source: McPherson - Henry’s Clinical Diagnosis and Management by Laboratory Methods, 24ed 2022