Oncohematology

AML Relapse: Dyserythropoiesis in Bone Marrow Aspirate

Morphological features of bone marrow in AML relapse: blast cells, megaloblasts, and severe dyserythropoiesis in a 66-year-old patient's aspirate.

A 66-year-old male. AML relapse. Smears were prepared from a bone marrow aspirate sent for IFT. In the smears, we observe blasts and a large number of normoblasts and megaloblasts with signs of dyserythropoiesis. The quality of the smears is suboptimal; the aspirate is hypocellular, and all large cells, unfortunately, ended up in the “brush” area of the smear.

👉 Photos and description kindly provided by Clinical Laboratory Diagnostics Physician, Pathologist, member of the FLM Hematology Committee Elena Belyakova, Department of Molecular Morphology, E.E. Eichwald Clinic, I.I. Mechnikov Northwestern State Medical University, St. Petersburg.