Platelet satellitism is an in vitro phenomenon in EDTA samples involving interaction with neutrophil CD16. Morphology of platelet adhesion in blood smear.
Platelet satellitism is considered an in vitro phenomenon occurring between platelets and neutrophils, which can sometimes also affect other leukocytes. CD16 (FCRIIIa) is a neutrophil receptor involved in this phenomenon when EDTA is used as an anticoagulant.
Sample type: Peripheral blood.
Staining type: May-Grünwald-Giemsa.
Author: A. Domingo Claros.
Workplace: Bellvitge University Hospital, Hospitalet de Llobregat, Barcelona.
Platelet satellitism as a laboratory phenomenon: platelet adhesion to neutrophils in EDTA blood smears and the risk of spurious thrombocytopenia.
EDTA-induced platelet aggregation is a common cause of spurious thrombocytopenia. Peripheral blood smear evaluation when analyzer shows 15×10^9/L.
Platelet satellitism in blood smear: platelet adhesion to neutrophils in EDTA-dependent pseudothrombocytopenia. Clinical case of a 71-year-old female patient.
