Hematology

Schistocytes in Blood Smear: Counting and Sysmex Detection

Morphology and counting of schistocytes in blood smears in microangiopathic hemolytic anemia. Evaluation of fragmented red blood cells (FRC) on Sysmex analyzers.

🩸Resuscitators: also check his blood for SCHISTOCYTES! 👉Photos 1,2,3: blood smear from a patient with microangiopathic hemolytic anemia - hemoglobin 80 g/L. Anemia: normocytic, normochromic. The smear shows more than 1% schistocytes (schistocytes, red blood cell fragments). Poikilocytosis (acanthocytes, keratocytes, spherocytes).

❗Did you know that according to international recommendations, SPHEROCYTES should also be included in the total count of schistocytes in a blood smear? We will tell you when this needs to be done at the Sunday class!

Schistocytes can also be detected on a hematology analyzer (photos 3-6). ✅Sysmex XN has such an additional complete blood count test - FRC* (Fragmented red blood cells)

👉Source: Kitchen S. et al. International Council for Standardization in Haematology (ICSH) recommendations for processing of blood samples for coagulation testing //International Journal of Laboratory Hematology. – 2021. – Т. 43. – №. 6. – С. 1272-1283.