🦟 Dengue Fever Diagnosis Using Sysmex XN Hematology Analyzer Blood Test WDF scattergrams from 8 different cases of dengue fever, showing a “figure 8” pattern for lymphocytes. The first figure in the series shows a population highlighted in gray, as cell population separation was poor. Legend: pink - lymphocytes, green - monocytes, light blue - neutrophils, orange - eosinophils
The study showed that the percentage of highly fluorescent lymphocytes (HFLC%) is a sensitive and early marker of dengue fever. In 87% of dengue patients, this indicator was above normal, especially on the 5th day of illness. On leukocyte scattergrams, such lymphocytes form a characteristic figure – a “figure eight” or “inverted hourglass”.
💡 HFLC% can be used for screening and dynamic monitoring in acute fevers, especially in resource-limited settings.
🔬 Large atypical lymphocytes with intense dark blue cytoplasmic staining; some cells show cytoplasmic projections. Found in blood smears from 6 different cases. 👉 Source: Jayaram A., - Elevated HFLC% and characteristic scattergrams on Sysmex XN analyzers as an early marker of dengue in acute fevers // Int J Lab Hematol. — 2021. — Vol. 43, No. 1. — P. 1–5 🩸 The full article from the international journal of laboratory hematology is available in the library of blood and bone marrow mysteries.
