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Oncohematology

AML and Plasma Cell Neoplasia Coexistence in Bone Marrow

A clinical case of simultaneous acute myeloid leukemia and plasma cell neoplasia: bone marrow cytomorphology and immunophenotyping.

Anna Belen Anna Belen 1 min
Bone marrow smear: blasts (red arrows) and plasma cells (green arrows)
Bone marrow smear: blasts (red arrows) and plasma cells (green arrows)
Bone marrow smear: hypercellular aspirate with blasts and plasma cells
Bone marrow smear: hypercellular aspirate with blasts and plasma cells
Bone marrow smear: proliferation of blast elements and plasma cells
Bone marrow smear: proliferation of blast elements and plasma cells
Bone marrow smear: plasma cells with eccentric nucleus among blasts
Bone marrow smear: plasma cells with eccentric nucleus among blasts
Bone marrow smear: atypical multinucleated plasma cells and leukemic blasts
Bone marrow smear: atypical multinucleated plasma cells and leukemic blasts
Bone marrow smear: initial field of view with blasts and plasma cells without arrows
Bone marrow smear: initial field of view with blasts and plasma cells without arrows

🔬Clinical case from a doctor from 🇮🇱Israel - Anna Belen Rare combination of AML and plasma cell neoplasia. Patient 85 years old. Mild pancytopenia in peripheral blood: WBC 3.25; HB 119; PLT 114. Photo of BM aspirate. Blasts - red arrows, plasma cells - green. His immunophenotyping shows 42% blasts CD34-/CD117dim/CD33dim/HLA-DR+/CD13-/CD38+/CD7+/CD64-/MPO-/cyCD79a-/cyCD3-. As well as a population of plasma cells with phenotype CD138+kappa/CD38+/CD117+/CD56-/CD19-/CD20-.

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