Hematology

Knyazkov-Dele Bodies in Neutrophils: Morphology and Significance

What Knyazkov-Dele bodies in neutrophils mean during blood smear microscopy. Morphological features, composition of inclusions, and connection to infections and inflammation.

Knyazkov-Dele bodies. Light blue, bluish inclusions in the cytoplasm of neutrophils. They consist of ribosomal RNA and remnants of the rough endoplasmic reticulum. They appear in reactive conditions (inflammatory, infectious processes).

Photos kindly provided by Vera Kirnas, Biologist at the Clinical Diagnostic Laboratory of the F.S. Ankudinov Yuzhno-Sakhalinsk City Hospital.