What are Howell-Jolly bodies in erythrocytes? Learn about the mechanism of nuclear remnant formation and their causes in megaloblastic anemia, hemolysis, and asplenia in blood smears.
🟣Howell-Jolly bodies (central erythrocyte with a round purple inclusion)
🔍Not an everyday finding in laboratory work
📖They are nuclear remnants that are normally removed during proper erythrocyte maturation.
May occur in:
🙏 The publication was kindly provided by Clinical Laboratory Diagnostics physician Tanya Stepanova, Volgograd.
What are Howell-Jolly bodies in a blood smear? Learn about the morphology of nuclear inclusions in red blood cells and their causes in asplenia, splenectomy, and hemolysis.
Morphological features of a blood smear in hereditary spherocytosis: microspherocytes, anisocytosis, Howell-Jolly bodies, and basophilic stippling of erythrocytes.
A clinical case of severe anemia (Hb 35 g/L): marked hypochromia, anisopoikilocytosis, basophilic stippling, Howell-Jolly bodies, and neutrophil hypersegmentation.
