Bone marrow morphology in MDS transforming to AML: 23% blasts, trilineage cytopenia, dysplasia, and cytochemical studies with MPO and PAS reaction.
Bone marrow smears from a 64-year-old patient diagnosed with MDS, with trilineage cytopenia in the periphery, 23% blasts, predominantly myeloid, some promyelocytic type cells, megaloblasts, inactive megakaryocytes. Transformation to AML is likely. Cytochemistry: MPO positive, PAS in diffuse form. Immunophenotyping recommended to confirm the diagnosis.
🙏 Publication kindly provided by laboratory physician Alla Alekseenkova, CHUZ Clinical Hospital RZD-Medicine, Smolensk.
Clinical case of MDS transforming to AML: 43% blasts, pronounced clasmatosis, signs of dyserythropoiesis, and cytochemical bone marrow results.
Cytological findings of bone marrow aspirate after AML treatment: hypocellularity, rare blasts, macrophages, and immature megakaryocytes.
A clinical case of acute myeloid leukemia: hyperleukocytosis, 71% blasts in bone marrow, positive myeloperoxidase, and diffuse PAS reaction.
