Oncohematology

Richter's Transformation: Lymph Node Imprint Cytology

Cytological features of a lymph node imprint in Richter's transformation to diffuse large B-cell lymphoma and its immunophenotype.

🔬Lymph node imprint cytology. Diffuse large B-cell lymphoma, non-GCB immunophenotype (Richter’s transformation). 💡Phenotype: CD20+ CD5+ CD23+ PAX5+ bcl-2+, LEF1+ mum1+; Not expressed: CD10, bcl-6, cyclin D1.

👉Images kindly provided by Clinical Laboratory Diagnostics physician, pathologist from St. Petersburg Elena Belyakova, Department of Clinical Molecular Morphology, E.E. Eichwald Clinic (Center for Differential Lymphoma Diagnostics), I.I. Mechnikov Northwestern State Medical University.