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Hemostasis

Severe Thrombocytopenia in HIV and Hepatitis C Co-infection

A clinical case of profound thrombocytopenia (PLT 3×10⁹/L) in HIV and hepatitis C co-infection: analyzer results and peripheral blood smear microscopy.

Olga Parfentyeva Olga Parfentyeva 1 min
Hematology analyzer printout: PLT 3×10⁹/L, MCV 67.4 fL, MCH 22.7 pg
Hematology analyzer printout: PLT 3×10⁹/L, MCV 67.4 fL, MCH 22.7 pg
Blood smear: lymphocyte against a background of marked absence of platelets
Blood smear: lymphocyte against a background of marked absence of platelets
Blood smear: mononuclear cells and complete absence of platelets
Blood smear: mononuclear cells and complete absence of platelets
Blood smear: disintegrated leukocyte, erythrocyte microcytosis without platelets
Blood smear: disintegrated leukocyte, erythrocyte microcytosis without platelets
Blood smear: small lymphocyte and erythrocyte hypochromia, no platelets found
Blood smear: small lymphocyte and erythrocyte hypochromia, no platelets found
Blood smear: monocyte and lymphocyte in the field of view, profound thrombocytopenia
Blood smear: monocyte and lymphocyte in the field of view, profound thrombocytopenia
Blood smear: marked thrombocytopenia, occasional poikilocytes and microcytes
Blood smear: marked thrombocytopenia, occasional poikilocytes and microcytes
Blood smear: disintegrated cell and erythrocyte anisocytosis without platelets
Blood smear: disintegrated cell and erythrocyte anisocytosis without platelets
Blood smear: lymphocytes in the field of view with no blood platelets
Blood smear: lymphocytes in the field of view with no blood platelets
Blood smear: field of view with hypochromic erythrocytes without platelets
Blood smear: field of view with hypochromic erythrocytes without platelets

⚠Decreased platelet count due to infection. ✅A 36-year-old male with severe thrombocytopenia, microcytic hypochromic anemia. History of HIV 4B + hepatitis C. ✅Complaints of persistent nosebleeds. ✅Analyzer PLT: 3 thou/µL. ❓How many platelets were found in the blood smears in the 9 photos below? 👉Case kindly provided by clinical laboratory diagnostics physician Olga Parfentyeva.

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