Oncohematology

Hairy Cell Leukemia: Cell Morphology and CBC Findings

A clinical case of hairy cell leukemia: morphology of hairy lymphocytes in a blood smear, cytopenias, and hematological analyzer data.

🔍 When lymphocytes grow “hairs”: progressive changes in CBC A 53-year-old male patient. When counting the leukocyte differential, 68% of lymphocytes are “hairy cells”: medium-sized; cytoplasm pale, grey-blue, with projections; nuclei round, chromatin structure homogeneous, smooth. Hematologist consultation recommended.

Repeated CBC a month later, with 81% “hairy cells” counted, also anemia, thrombocytopenia, absolute lymphocytosis, and neutropenia.

🙏 The publication was kindly provided by Tatyana Klyukina, a clinical laboratory diagnostics physician, St. Petersburg.