Oncohematology

Hairy Cell Leukemia: Blood Smear Cell Morphology

A clinical case of hairy cell leukemia: morphology of hairy lymphocytes with characteristic cytoplasmic projections in a blood smear and hemogram parameters.

Blood smear: hairy cell leukemia, lymphocytes with thin cytoplasmic projections
Blood smear: hairy cell leukemia, lymphocytes with thin cytoplasmic projections

Hairy Cell Leukemia Hairy cells with peripheral hairy projections in a peripheral blood smear.

Laboratory evaluation was significant for the following:

  • Red blood cell count 6.29 × 10^12/L
  • White blood cell count 32.46 × 10^9 /L (neutrophils: 10%, lymphocytes: 88% (hairy cells: 72%))
  • Hemoglobin 18.3 g/dL
  • Hematocrit 52.8%
  • Mean corpuscular volume 84.0 fL
  • Mean corpuscular hemoglobin 29.1 pg
  • Platelet count 145 × 10^9 /L

Author: Dr. Nader Vazifeh Shiran, PhD; Nima Torabi Fard, PhD Category: Lymphoma: Mature B-cell and Plasma Cell Neoplasms > Splenic Lymphomas > Hairy Cell Leukemia Publication Date: 16.10.2024

Photo source: ASH image bank