Oncohematology

Hematology Case: Retinal Vein Occlusion and Paraprotein

Clinical case: A 69-year-old patient presents with retinal vein occlusion, lymphadenopathy, IgM paraprotein, and bone marrow changes. Determine the diagnosis.

Hematology Case A 69-year-old man presented to an ophthalmologist with sudden vision loss. The ophthalmologist found retinal vein thrombosis (branch occlusion). He also noticed enlarged lymph nodes on the right side of his neck. He had no other abnormal physical signs. He was generally healthy. Complete blood count: Hb 98 g/L WBC 7.6 x 10 (9)/L Other tests show: Total protein 94 g/L. Protein electrophoresis shows a paraprotein identified as IgM kappa (36 g/L) Bone marrow aspirate microscopy is shown in the photo below. What is the most likely diagnosis? Vote. The answer will be in the group news tomorrow.