Hematology
Neutrophil Vacuolization: Causes and Clinical Significance
What neutrophil vacuolization in a blood smear means: a marker of severe bacterial infection, sepsis, or an artifact of prolonged EDTA sample storage.
Tag
Analysis Artifacts
Hematology
Unusual Red Blood Cell Aggregation in Peripheral Smear
An unusual radial aggregation of red blood cells in a peripheral blood smear. Features of red blood cell morphology assessment and laboratory artifacts.
Hematology
Endothelial Cells in Peripheral Blood Smear: Morphology
Morphology of endothelial cells in blood smears during severe conditions and intoxications: identifying features and differential diagnosis with atypical cells.
Laboratory methods
Yeast-like Fungi Contamination in Blood Smears
Yeast-like organisms in blood smears as a result of contamination during sample collection or staining. Analysis of a preanalytical error in clinical practice.
Hematology
Cold Agglutination in Complete Blood Count: A Case Study
A case of cold agglutination: false MCHC elevation, sample appearance in tube and microscopy, and parameter correction after 37°C incubation.
Hematology
Bacteria in Blood Smear: Contamination or Bacteremia?
How to distinguish bacterial contamination and staining artifacts from true bacteremia during peripheral blood smear microscopy: a case study.
Hematology
Differential Diagnosis of Granulated Cells in Blood Smears
Morphological evaluation of highly granulated cells in blood smears during leukocytosis: differential diagnosis of granulocytes and staining effects.
Hematology
Artifacts and Inclusions in Lymphocyte Cytoplasm
How to distinguish true cytoplasmic inclusions from fixation and staining artifacts in a blood smear: morphological features and differential diagnosis.
Laboratory methods
Blood Smear Artifacts from Underfilled EDTA Tubes
How excess EDTA in small blood volumes distorts analyzer scattergrams and cell morphology: echinocytes, nuclear pyknosis, and endothelial aggregates.
Parasitology
Microfilariae Suspicion vs. Artifacts in Blood Smear
Unusual spiral inclusion in a peripheral blood smear: differential diagnosis of microfilariae and laboratory artifacts in light microscopy.
Hematology
Unusual Erythrocyte Morphology Artifacts in Blood Smears
Erythrocyte morphology and artifacts in peripheral blood smears: evaluating cell shape, causes of artifactual clearings and fixation defects.