Basophilic Stippling on Leukoformula

Basophilic Stippling of Erythrocytes in P5'N Deficiency

Tue, 06 Oct 2026 16:00:01 +0300

The correct answer to the challenge from the closed club of laboratory hematologists. B. Basophilic stippling of erythrocytes. The presence of polychromatophilic macrocytes with prominent (from fine to coarse) basophilic stippling in the presence of congenital hemolytic anemia is characteristic of pyrimidine-5’-nucleotidase (P5’N) deficiency. 🏆 Congratulations to the winners!

Basophilic Stippling of Erythrocytes in a Blood Smear

Mon, 05 Oct 2026 17:25:47 +0300

💡 A task from the closed club of laboratory hematologists. Examine the peripheral blood smear of a patient with congenital hemolytic anemia and pronounced reticulocytosis. Identify the morphological feature of erythrocytes shown in the image.

Blood Smear in B12 Deficiency Anemia: Morphology

Tue, 24 Mar 2026 08:00:00 +0300

A patient from the hematology department. Complaints of weakness, lethargy, pallor of the skin, and loss of appetite. Suspected B12 deficiency anemia, possibly in combination with folate deficiency. Peripheral blood - reticulocytes 115 per mille. Hemoglobin 61g/L, erythrocytes 1.7 *10/12/L, thrombocytopenia, normocytes 22:100, with altered nuclear configuration, polychromasia of erythrocytes, multiple Howell-Jolly bodies, basophilic stippling of erythrocytes.

Basophilic Stippling of Erythrocytes in Blood Smear

Fri, 27 Dec 2024 10:00:07 +0300

🔬 What can be observed in this blood smear microscopy image from a patient with anemia?

🙏The image was kindly provided by Anna Ivanova, a physician in clinical laboratory diagnostics, Anna Ivanova, Moscow.

Basophilic Stippling of Erythrocytes in Blood Smear

Wed, 18 Dec 2024 17:00:00 +0300

🔬 Basophilic stippling of erythrocytes.
In adults, mild basophilic stippling has no specific diagnostic significance, similar to anisocytosis, and only indicates a non-specific reactive process. The detection of a large number of erythrocytes with basophilic stippling has diagnostic significance in thalassemia, lead poisoning, and sideroblastic anemia of any genesis.

🙏 Photos and description were kindly provided by biologist [Anna Feditskaya](https://vk.com/id147033613), Luhansk.

Congenital Dyserythropoietic Anemia in Blood Smear

Thu, 04 Jul 2024 16:20:00 +0300

Congenital dyserythropoietic anemia (CDA). A clinical case from 🇮🇱 Israel. Blood was received from a 5-year-old girl for a prophylactic examination. History of b-thalassemia minor. The morphological picture did not correspond at all to the known diagnosis! Complete blood count parameters can be found at the end of the photo carousel below. The smear showed marked aniso- and poikilocytosis! The child was referred for further genetic testing, where CDA was confirmed! What conditions/diseases should we differentiate it from? What erythrocyte shapes and inclusions do we note?

Howell-Jolly Bodies & Basophilic Stippling in Blood Smears

Tue, 16 Jun 2020 12:54:05 +0300

A 52-year-old female, numerous Howell-Jolly bodies, basophilic stippling HGB - 122 g/L RBC - 3.09 M/µL HCT - 34.1% MCH - 39.5 pg MCHC - 358 g/L MCV - 110.4 fL RDW-CV - 15.8% RDW-SD - 63 fL