Parasitology
Entamoeba coli Cysts: Morphology and Distinguishing Features
Criteria for identifying Entamoeba coli cysts by microscopy: size, more than four nuclei, eccentric karyosome, and splinter-shaped chromatoid bodies.
Tag
Differential Diagnosis
Hematology
Diagnostic Algorithm for Microcytic Hypochromic Anemia
Laboratory algorithm for differential diagnosis of microcytic hypochromic anemias: ferritin, iron, TIBC, and transferrin saturation.
Parasitology
Helminth Eggs: Morphology and Size in Microscopy
A differential diagnostic table for parasite eggs: microscopic features and sizes of trematode, cestode, and nematode eggs in laboratory practice.
Oncohematology
Plasma Cells in Blood Smear in Multiple Myeloma
A clinical case of detecting 6% plasma cells in a complete blood count in myeloma before bone marrow aspiration and a sharp increase in free lambda chains.
Laboratory methods
Myelin in Nail Samples: Distinguishing from Fungal Spores
Microscopy of nail scrapings with 20% KOH: why myelin is mistaken for fungal spores, morphological differences of artifacts, and sample preparation features.
Lab test interpretation
Microscopy of Flora Smear: Inclusions in Squamous Epithelium
Analysis of flora smear microscopy: squamous epithelial cells, rod-shaped flora, and differential diagnosis of intracellular inclusions versus staining artifacts.
Parasitology
Morphology of Fasciola hepatica and Fasciolopsis buski Eggs
Morphology of Fasciola hepatica and Fasciolopsis buski eggs: over 100 µm, operculum detection, and differentiation from similar helminth eggs.
Hematology
Exercise: Find the Leukocyte Among Normoblasts in Cell Gallery
Clinical digital microscopy exercise: identify the misclassified leukocyte in a gallery of normoblasts (NRBCs) in hemolytic disease of the newborn.
Lab test interpretation
Calcium Oxalate Crystals in Urine Sediment at pH 5.5
Morphology of crystals in urine sediment with an acidic reaction (pH 5.5): differential diagnosis of calcium oxalate monohydrate and dihydrate during microscopy.
Lab test interpretation
Acanthocytes in Urine: Marker of Glomerular Hematuria
Morphology and diagnostic significance of acanthocytes in urine. Presence of >5% acanthocytes as a marker of glomerular hematuria during sediment microscopy.
Parasitology
Myxozoa Spores in Stool: Distinguishing from Spermatozoa
Myxozoa (Henneguya) fish parasite spores in human stool: causes of detection, morphology, and differentiation from spermatozoa during microscopy.
Lab test interpretation
Stool Microscopy: Object Identification Challenge
A clinical coprogram challenge: microscopy of a 30-year-old woman's stool revealed objects approximately 50 µm long. Try to identify them.