Essential Thrombocythemia on Leukoformula

Giant Megakaryocytes in Bone Marrow with Thrombocytosis

Mon, 18 May 2026 09:00:01 +0300

GIANT MEGAKARYOCYTES in bone marrow aspirate from a 57-year-old female patient examined for THROMBOCYTOSIS (PLT 897×10^9/L). Peripheral blood (photos 8,9).

🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZD-Meditsina, Smolensk.

Giant Platelets in Secondary Myelofibrosis

Sat, 20 Sep 2025 14:14:20 +0300

Patient, 72 years old. Diagnosis: essential thrombocythemia progressing to secondary myelofibrosis. Large platelets in the blood smear. 🙏 Photos kindly provided by Vera Kirnas, Biologist, Clinical Diagnostic Laboratory, Yuzhno-Sakhalinsk City Hospital named after F.S. Ankudinov

Neutrophil Hypersegmentation: Causes and a Clinical Case

Thu, 31 Oct 2024 20:00:01 +0300

🔬 Neutrophil Hypersegmentation in a Blood Smear A 72-year-old woman was admitted with acute bronchitis. History: essential (hemorrhagic) thrombocythemia. 🩸 CBC Results: ✅ Leukocytes (WBC): 16.27 × 10⁹/L (normal 4.0 – 9.0 × 10⁹/L) – leukocytosis here likely indicates acute inflammation. ✅ Erythrocytes (RBC): 2.88 × 10¹²/L (normal 3.5 – 5.5 × 10¹²/L) – low values, possible signs of anemia. ✅ Hemoglobin (HGB): 115 g/L (normal 120 – 160 g/L) – anemia ✅ MCV: 119.10 fL – macrocytic anemia ✅ Platelets (PLT): 805 × 10⁹/L (normal 150 – 400 × 10⁹/L) – thrombocytosis, confirming the diagnosis of essential thrombocythemia. ✅ Neutrophils (NEUT#): 14.49 × 10⁹/L (normal 2.0 – 7.5 × 10⁹/L) – elevated count, characteristic of bacterial infection. ✅ ESR: 60 mm/h (normal 2 – 20 mm/h) – indicates the presence of an inflammatory process. MCV 119.10 📊 Interpretation: This picture is typical for an infectious-inflammatory process complicating the patient’s chronic blood disorder. Such a case requires careful monitoring and a comprehensive approach to treatment, considering both the underlying disease and the concomitant infection.