Herpes on Leukoformula

Herpes Virus Cytopathic Effect in Cervical Smear

Fri, 03 Apr 2026 15:00:01 +0300

Multinucleated epithelial cell in herpesvirus infection.

Morphological features:

Presence of multiple nuclei with the phenomenon of “molding” (close apposition of nuclei to each other without clear boundaries).
Basophilic intranuclear inclusions, separated from the thickened nuclear membrane by a clear zone (perinuclear halo).

Context: This image illustrates the cytopathic effect of Herpes simplex virus in cervical epithelial cells.

Tzanck Smear in Herpetic Stomatitis: Cytology

Wed, 31 Jul 2024 10:41:00 +0300

Tzanck smear in herpetic stomatitis. Note the multinucleated epithelial giant cells from a patient with herpes simplex virus infection. Source: Jean L. Bolognia - Dermatology Volume 1 5th Edition 2024

Herpes Simplex Virus in Cervical Cytology

Sun, 07 Jul 2024 09:41:00 +0300

🔬 Cervix. Herpes simplex virus. Educational material from the Department of Clinical Laboratory Diagnostics, RMACPE.

large multinucleated cells (up to 60 µm in diameter)
chromatin structure is blurred (ground-glass appearance)
nuclear membrane is clearly contoured
nuclear crowding, “mulberry” phenomenon

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