
Laboratory methods
Shubich Method: Granulocyte Cationic Protein Detection
The principle of Shubich's cytochemical reaction with bromophenol blue: detecting cationic lysosomal proteins as granules in the cytoplasm of blood neutrophils.
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The principle of Shubich's cytochemical reaction with bromophenol blue: detecting cationic lysosomal proteins as granules in the cytoplasm of blood neutrophils.

A clinical case of CML detected during a routine blood test: hyperleukocytosis 203×10⁹/L, thrombocytosis, granulocyte maturation stages, and BCR-ABL1 mutation.

A practical laboratory hematology exercise: evaluating cell morphology in a blood smear. Test your skills in differential diagnosis of precursors.

Morphological evaluation of highly granulated cells in blood smears during leukocytosis: differential diagnosis of granulocytes and staining effects.