
Cold Agglutination of Erythrocytes: Mechanism and Elimination
What are cold agglutinins, how do they cause red blood cell clumping, and how to eliminate agglutination by warming a blood tube to 37°C in the lab.
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What are cold agglutinins, how do they cause red blood cell clumping, and how to eliminate agglutination by warming a blood tube to 37°C in the lab.

Results of C1s complement inhibitor sutimlimab in cold agglutinin disease: dynamics of hemoglobin, bilirubin, and reticulocytes.

Impact of cold autoimmune hemolytic anemia on analyzer parameters: erythrocyte agglutination, false MCHC, and correction by warming at 37 °C.

Blood smear morphology in Mycoplasma pneumoniae: severe cold agglutination of red blood cells, falsely elevated MCHC, and reactive lymphocytes with uropods.

A case of cold agglutination: false MCHC elevation, sample appearance in tube and microscopy, and parameter correction after 37°C incubation.

What to do if MCHC is elevated above 375 g/L in CBC: causes of false elevation, cold agglutination, sample warming, and blood smear evaluation.

Blood smear morphology in cold autoimmune hemolytic anemia (CAIHA). Mechanisms of erythrocyte agglutination by IgM antibodies to I and i antigens.

Impact of cold agglutination on CBC parameters: falsely elevated MCHC, spurious erythrocytopenia, and correction by warming to 37 °C.

Cold agglutinin disease: mechanism of autoimmune hemolysis by IgM antibodies, symptoms, and features of cold agglutination of erythrocytes in blood tests.