
Differential Diagnosis of Blasts and Lymphocytes in Blood
Morphological features of blasts in blood: high nuclear-cytoplasmic ratio, delicate chromatin, and the role of immunophenotyping in diagnosis.
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Morphological features of blasts in blood: high nuclear-cytoplasmic ratio, delicate chromatin, and the role of immunophenotyping in diagnosis.

Clinical case: atypical mononuclear cells (32%) and leukocytosis 21.38×10⁹/L in a 23-year-old female patient. Sysmex WDF and WPC scattergrams, cytology, and leukocyte differential.

Morphological features of blasts in acute lymphoblastic leukemia L3 (FAB) and Burkitt lymphoma: cytoplasmic basophilia, pronounced cell vacuolization.

Clinical case of CML: 7% blasts, myelocytes, and metamyelocytes in CBC. Cell morphology and the importance of blast count in myeloid leukemia.

Clinical case of acute myeloid leukemia in a 15-year-old teenager: Auer rods in blasts, pancytopenia, leukocytosis, and analyzer scattergram.

Clinical case analyzing blast morphology in a blood smear: identifying deep clefts, nuclear lobulation, binuclearity, and chromatin structure assessment.

Detection of 12% blasts in leukopenia and severe thrombocytopenia. Features of blood smear microscopy and analyzer scattergram in pancytopenia.

A clinical case of leukemia in a 63-year-old female: leukocytosis, 73% blasts, and the value of reticulated platelet analysis for early diagnosis.

A clinical case of acute erythroid leukemia (AML M6): blasts and severe dyserythropoiesis in bone marrow, cytochemical glycogen study.

A clinical case of acute promyelocytic leukemia (AML M3) diagnosis, including blood and bone marrow cell morphology, cytochemistry (MPO, PAS), and PML/RARa translocation detection.

Features of differential leukocyte count in severe leukopenia: detection of large granular lymphocytes, WDF scattergram analysis, and digital microscopy.

Causes of spurious thrombocytopenia on the analyzer: detection of large platelet aggregates in EDTA blood smear and rules for re-collection in a citrate tube.