Hematology
Platelet Formation and Fate of Mature Megakaryocyte Nucleus
How blood platelets are formed: a diagram of megakaryocyte cytoplasm fragmentation and phagocytosis of its residual nucleus by bone marrow macrophages.
Tag
Bone Marrow
Laboratory methods
Myelogram Cell Count: 300 or 500 Cells in Bone Marrow Smear
How many cells to count for a myelogram: comparing WHO recommendations for 500 cells and data on differentiating 300 bone marrow aspirate cells.
Oncohematology
Pawn Ball Megakaryocytes in Myelodysplasia
Explore the morphological features of pawn ball megakaryocytes in myelodysplastic syndrome. Understand the diagnostic significance of dysmegakaryocytopoiesis in bone marrow smears.
Hematology
Bone Marrow as a Hematopoietic Organ: History of Discovery
Explore the history of hematopoiesis: Ernst Neumann's 1868 discovery of bone marrow's role and Mikhail Arinkin's 1928 introduction of in vivo bone marrow puncture.
Hematology
Myelogram Indicators in Hematological Diseases
Comparative table of myelogram changes in anemias, infections, leukemias, and agranulocytosis, contrasted with normal bone marrow indicators.
Oncohematology
Mitotic Figures and Dyserythropoiesis in MDS with Excess Blasts
Clinical case of MDS with excess blasts: bone marrow erythroblast morphology, multinuclearity, atypical mitotic figures, and micronuclei formation.
Hematology
Osteoclasts in Bone Marrow Aspirate: Differential Diagnosis
Morphological features of osteoclasts in bone marrow aspirate. Differential diagnosis of multinucleated osteoclasts and megakaryocytes in a smear.
Oncohematology
Acute Promyelocytic Leukemia: Hypogranular Variant M3v
Morphology of atypical promyelocytes in hypogranular acute promyelocytic leukemia M3v: bilobed nuclei resembling butterfly wings in bone marrow.
Oncohematology
Chronic Neutrophilic Leukemia: Bone Marrow Aspirate
A clinical case of chronic neutrophilic leukemia: hyperleukocytosis, granulocyte hyperplasia, and phagocytosis of nuclear debris by bone marrow macrophages.
Oncohematology
Acute Lymphoblastic Leukemia B-IV: Morphology and Immunophenotyping
A case of B-IV acute lymphoblastic leukemia: blast morphology in bone marrow, myeloperoxidase cytochemistry, and immunophenotyping results.
Oncohematology
Bone Marrow Plasmacytes in Multiple Myeloma
Morphological features of plasmacytes in a myelogram in multiple myeloma: eccentric nucleus, basophilic cytoplasm, and perinuclear halo.
Hematology
Electron Microscopy: Identify the Bone Marrow Cell
A diagnostic challenge in cell morphology: identify the hematopoietic bone marrow cell in this transmission electron micrograph (×13,000).