https://www.leukoformula.com/en/tags/mastocitoz/Recent content in Mastocytosis on LeukoformulaHugoen-USSat, 22 Jul 2023 19:37:48 +0300https://www.leukoformula.com/en/post/sistemnyy-mastocitoz-klinicheskiy-sluchay-i-12586/Sat, 22 Jul 2023 19:37:48 +0300https://www.leukoformula.com/en/post/sistemnyy-mastocitoz-klinicheskiy-sluchay-i-12586/<p>⚠Systemic mastocytosis. Clinical case. ✅A 42-year-old male with significant splenomegaly, hepatomegaly, and urticaria pigmentosa-like skin rash. 🔬Peripheral blood showed mild anemia: hemoglobin 113 g/L and leukopenia 3.11×10^9/L. ✅Bone marrow aspiration for IFT failed. Touch imprints from the trepanobiopsy were made: we see clusters of atypical mast cells. ❗Blood tryptase &gt;200 µg/L (N = 0-11.4) – a marker of mast cell activation, a marker of mastocytosis. ✅Histology showed bone marrow infiltration by mast cells positive for CD117, CD25, CD2.</p>