Sputum on Leukoformula

Pseudomycelium in Sputum: Ziehl-Neelsen Staining

Sat, 29 Aug 2026 08:00:00 +0300

Pseudomycelium. Sputum smear. Ziehl-Neelsen staining

🙏 The publication was kindly provided by Kristina Goncharova

Ziehl-Neelsen Staining for Acid-Fast Bacilli in Sputum

Fri, 24 Jul 2026 15:17:10 +0300

Hello, I’m not a sputum specialist, could you please tell me if this is AFB? I’m just starting to learn and observe. The material is sputum, Ziehl-Neelsen stain.

Curschmann's Spirals in Sputum: Microscopic Findings

Tue, 21 Jul 2026 08:00:00 +0300

Curschmann’s spiral in a patient’s sputum‼️ One, but very large. The first photo is x20 magnification, subsequent ones are x40.

🙏 The publication was kindly provided by Ekaterina Nozdrina, Omsk.

Alveolar Macrophages in Native Sputum Preparations

Mon, 08 Jun 2026 09:00:01 +0300

Alveolar macrophages (sputum microscopy).

🙏 This publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZHD-Meditsina", Smolensk.

Charcot-Leyden Crystals in Sputum: A Microscopic Case Study

Tue, 28 Apr 2026 08:00:00 +0300

A patient from cardiology. History includes chronic bronchitis, COPD, ill for 3 weeks, admitted with a picture of developing pulmonary edema. ECG revealed ACS with ST elevation in the anteroseptal region. MSCT showed bilateral polysegmental pneumonia. Material: sputum. A large number of Charcot-Leyden crystals were found.

Curschmann's Spirals in Sputum in Bronchial Asthma

Mon, 13 Apr 2026 09:00:01 +0300

Curschmann’s spiral in a native sputum smear from a patient with bronchial asthma. Objective ×20

🙏 The publication was kindly provided by Alexey Degtyarev

Bronchial Lavage Cytology: Neutrophils and Inflammation

Mon, 30 Mar 2026 09:00:01 +0300

NEUTROPHILS in bronchial lavage fluid.

🙏 This publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZD-Meditsina, Smolensk.

Curschmann's Spirals in Sputum: COPD and Pneumonia

Fri, 27 Mar 2026 10:00:00 +0300

A man with pneumonia. He has suffered from COPD for more than 10 years, experiencing shortness of breath and cough with minimal physical exertion. Material - sputum. Curschmann’s spirals.

Mycobacterium Tuberculosis in Sputum Smear: Ziehl-Neelsen Stain

Tue, 03 Mar 2026 08:00:00 +0300

Mycobacterium tuberculosis in Sputum

🙏 Photos kindly provided by Inna Storozheva, Clinical Diagnostic Laboratory of the Regional Hospital, Kaliningrad.

Curschmann's Spirals in Native Sputum Preparation

Fri, 27 Feb 2026 09:00:00 +0300

Curschmann’s spiral. Native sputum preparation. Pulmonology. 40x magnification. Patient with pneumonia, HIV-infected.

🙏 The publication was kindly provided by Ekaterina Nozdrina, Omsk.

Creola Bodies in Sputum in Bronchial Asthma

Tue, 17 Feb 2026 12:00:00 +0300

Creola bodies in a native sputum smear. Magnification x40. Patient from the pulmonology department. Creola bodies are clusters of columnar alveolar epithelium in bronchial asthma. They are often considered an unfavorable sign. This patient, in principle, had a large number of columnar epithelial cells, some of which clumped together into such “clumps”. Often, cilia are still present at the edges of Creola bodies; in a native smear under a coverslip, it is often visible how they perform their ciliary movements.

Cylindrical Epithelium in Sputum: Ziehl-Neelsen Staining

Tue, 10 Feb 2026 08:00:00 +0300

Delicate cylindrical epithelial cells in the sputum of a pulmonology patient, Ziehl-Neelsen stain.

🙏 The publication was kindly provided by Ekaterina Nozdrina, Omsk.

Smoker's Cells in Sputum: Alveolar Macrophages

Sat, 31 Jan 2026 08:00:00 +0300

Patient of the pulmonology department with a diagnosis of pneumonia, COPD. Known to smoke 1-2 packs a day for 35 years. Material - sputum. Kinyoun stain. Alveolar macrophages with black inclusions are visible in the field of view. “Smoker’s cells”

Alveolar Macrophages in Native Sputum Smear

Wed, 28 Jan 2026 08:00:01 +0300

A large number of alveolar macrophages in a native sputum smear..

🙏 Publication kindly provided by Alla Alekseenkova

Charcot-Leyden Crystals in Sputum: Microscopic Analysis

Fri, 26 Dec 2025 20:00:00 +0300

Charcot-Leyden crystals. Sputum, mag.×400. 67-year-old patient, chronic bronchitis

🙏Image kindly provided by biologist Natalia Morkhova

Cylindrical Epithelium in Sputum Analysis

Thu, 27 Nov 2025 20:00:00 +0300

General sputum analysis, cylindrical epithelium in some patients. Mag. 40x

🙏 Publication kindly provided by Ekaterina Nozdrina, Omsk.

Charcot-Leyden Crystals in Native Sputum Preparations

Fri, 14 Nov 2025 10:30:27 +0300

Colorless Charcot-Leyden crystals in a native sputum preparation 😍

🙏 This publication was kindly provided by Ekaterina Nozdrina, Omsk.

Acid-Fast Mycobacteria and Curschmann's Spirals in Sputum

Wed, 29 Oct 2025 12:59:00 +0300

🔬✨ Pulmonology and thoracic surgery under the microscope. Acid-fast mycobacteria are frequent “guests” in laboratory smears from these departments.

And in the last photo – a coincidental but very beautiful finding: Curschmann’s spiral. An elegant convoluted mucin thread, appearing in bronchial asthma and bronchial inflammation.

Mold Mycelium in Sputum Microscopy: Lab Diagnostics

Mon, 13 Oct 2025 08:00:01 +0300

Mold mycelium in sputum. 🙏 This publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZHD-Medicine, Smolensk.

Curshmann's Spirals in Native Sputum Smear: A Case Study

Thu, 18 Sep 2025 09:05:45 +0300

Huge Curshmann’s spirals in a native sputum smear. Male, 80 years old, chronic bronchitis. Photos 1-4: 100x magnification, photo 5: 400x magnification, photo 6: no magnification (spirals are visible to the naked eye, do not disintegrate when pressing on the coverslip).

Charcot-Leyden Crystals in Native Sputum Preparation

Wed, 03 Sep 2025 12:00:20 +0300

Abundance of Charcot-Leyden crystals in sputum. Native preparation, 400x magnification. 🙏Images kindly provided by biologist Natalia Morhova

Curschmann Spirals in Sputum: Microscopy and Diagnosis

Wed, 06 Aug 2025 18:00:00 +0300

Curschmann spirals in a sputum sample.

Curschmann spirals are twisted mucoprotein structures formed in small bronchi due to hypersecretion of mucus and impaired clearance. They are more common in chronic inflammatory diseases of the respiratory tract (e.g., bronchial asthma, chronic bronchitis).

Acid-Fast Bacilli (AFB) in Sputum Smear

Tue, 29 Jul 2025 08:16:25 +0300

AFB in sputum

🙏 Images kindly provided by laboratory physician Alena Chirvina, Rostov-on-Don

Atypical Cells in Sputum Cytology Smear

Mon, 09 Jun 2025 21:31:32 +0300

Man, born 1955. Microscopy of bloody sputum. Cells with marked atypia were found. Romanowsky stain.

🙏 Images were kindly provided by KDL biologist Yulia Guseva, GBUZ Belorechenskaya Central District Hospital.

Sputum Microscopy: Identify Inclusions in the Specimen

Mon, 07 Apr 2025 19:00:01 +0300

Anonymous question from a subscriber. Sputum, native specimen. Presumably starch grains…

More precise assumptions are WELCOME! 💪❤

Oral Trichomonas tenax in a Sputum Smear

Mon, 07 Apr 2025 16:00:08 +0300

A finding in a native sputum preparation! Oral Trichomonas. The 3rd photo shows a preparation stained according to Romanowsky. The patient is antisocial. He also tested positive for AFB 1+.

Mycobacterium Tuberculosis in Sputum: Ziehl-Neelsen Stain

Tue, 04 Feb 2025 17:00:29 +0300

🔬 Mycobacterium tuberculosis in a sputum sample. Ziehl-Neelsen stain. Confirmed by culture and PCR.

🙏 Case kindly provided by Vera Kirnas Biologist, Clinical Diagnostic Laboratory, F.S. Ankudinov Yuzhno-Sakhalinsk City Hospital

Coniophages and Alveolar Macrophages in Sputum Microscopy

Mon, 20 Jan 2025 18:30:00 +0300

Alveolar macrophages – “smoker’s cells” or “dust cells” (coniophages). Coniophages phagocytose dust, soot, nicotine, paint, and other particles. These inclusions are visible in the cell cytoplasm in native smears as yellowish-brown, brown, black, and colored granules of various sizes. Sometimes there are so many inclusions that they practically fill the entire cytoplasm. For example, alveolar macrophages in the sputum of miners can be black due to coal microparticles, in millers – white, and in people working in paint production – multicolored. In thick and viscous sputum, when preparing a smear for staining, the cells stretch along the mucous strand. Magnification 40× and 10×.

Perls' Reaction in Sputum: Heart Failure Cells

Mon, 30 Dec 2024 14:30:00 +0300

Positive Perls’ reaction in alveolar macrophages. Perls’ reaction is a method for detecting trivalent iron within hemosiderin and ferritin. The reagents used are potassium ferrocyanide and hydrochloric acid of equal concentration (5%) and equal volume. Hydrochloric acid ensures the availability of the iron cation by breaking down hemosiderin and forming iron(III) chloride. Iron chloride, in turn, reacts with the potassium ferrocyanide solution, forming a mixture of hexacyanoferrates(II) – pigments collectively known as Prussian blue. In laboratory diagnostics and histology, this reaction is used to detect hemosiderin in macrophages. Alveolar macrophages laden with hemosiderin are called “heart failure cells”. Such cells originate from alveolar septal macrophages that have engulfed erythrocyte debris, with hemoglobin being converted into hemosiderin. Heart failure cells accumulate in the alveolar lumen during pulmonary congestion. Sputum smear, stained with Perls’ reaction. Magnification x100, x200, x400

Fungal Mycelium in Native Sputum Smear Microscopy

Tue, 24 Dec 2024 12:00:02 +0300

🍂 “Tree with falling leaves.” 🔬 Mycelium amidst erythrocytes in a native sputum smear. Magnification 400x and 100x.

🔬 Material kindly provided by biochemist Daniil Adamov, Moscow