Normoblasts on Leukoformula

Howell-Jolly Bodies & Binucleated Normoblasts in Blood Smear

Tue, 02 Jun 2026 09:00:00 +0300

Newborn infant.

Peripheral blood. Erythrocyte with a Howell-Jolly body (photo 1) and a binucleated normoblast with a Howell-Jolly body (photo 2).

🙏 The publication was kindly provided by Ekaterina Nozdrina, Omsk.

Bone Marrow Erythroid Lineage in Multiple Myeloma

Mon, 11 May 2026 08:00:00 +0300

Patient, 71 years old, diagnosed with multiple myeloma.

Complete blood count:

RBC 3.6×10^12/L

HGB 128 g/L

WBC 4.0 g/L

PLT 210×10^9/L

ESR 18 mm/hour.

In the control bone marrow aspirate, after a course of treatment, the erythroid lineage of hematopoiesis is expanded to 47.5% (normal range 14.5-26.5). Binucleated erythrokaryocytes (photo 2, 3) and mitotic figures (photo 5) are observed.

Bone Marrow Erythroid Hyperplasia in Splenomegaly Case

Sat, 25 Apr 2026 08:00:00 +0300

SPLENOMEGALY in a 56-year-old PATIENT. Complete blood count without abnormalities: RBC 4.66×10^{12/L
HGB 142 g/L
WBC 3.43×10}9/L PLT 149 ×10^9/L.

In the bone marrow aspirate, the granulocytic lineage is relatively narrowed (35.4%), lymphocytes are 13.5% (normal 4.3-13.7%), and erythrocaryocyte proliferation is significantly increased (45.0%). Binucleated erythrocaryocytes are observed. Megakaryocytes show preserved functional capacity.

Proerythroblast: Morphological Features of the Cell

Tue, 14 Apr 2026 08:00:00 +0300

PROERYTHROBLAST is a young, large cell of the erythroid lineage of hematopoiesis, with a round nucleus containing delicate reticular chromatin, a nucleolus, and intensely basophilic cytoplasm.

🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZHD-Meditsina", Smolensk.

Blood Smear in Beta-Thalassemia Post-Splenectomy

Thu, 19 Mar 2026 09:00:01 +0300

👉🏻Severe anisopoikilocytosis in a patient with beta-thalassemia and splenectomy.

➖This is a hereditary blood disorder in which the synthesis of beta-globin chains is impaired.

🩸Peripheral blood

🔹The smear contains target cells (codocytes) characteristic of thalassemia (photo 1)

Autoimmune Hemolytic Anemia: Blood Smear Morphology

Wed, 25 Feb 2026 18:00:00 +0300

Autoimmune hemolytic anemia caused by warm antibodies

Polychromasia and spherocytes are found in the peripheral blood; circulating erythroblasts and occasional Howell-Jolly bodies may be present.

The disease is caused by immunoglobulin G class antibodies that react with red blood cells at temperatures of 37 degrees Celsius and above. This is the most common form of autoimmune hemolytic anemia.