Pleural Fluid on Leukoformula

Eosinophils in Pleural Fluid: Cytology of Effusion

Wed, 26 Aug 2026 08:00:00 +0300

Eosinophils in pleural fluid!

🙏 This publication was kindly provided by Anastasia Yasyreva

Signet Ring Cells in Pleural Fluid Smear: A Case Study

Wed, 22 Apr 2026 09:00:01 +0300

In the pleural fluid smear, signet ring cells are present. The patient has a diagnosis of chronic cerebral ischemia. Stained with Romanowsky-Giemsa.

🙏 The publication was kindly provided by biologist Karina Bikasheva, Luhansk People’s Republic.

Cytological Features of Adenocarcinoma in Pleural Effusion

Fri, 17 Apr 2026 09:00:01 +0300

Material - pleural effusion. A patient was admitted to the department when pleural effusion was detected during a routine fluorography. She does not smoke, has never smoked, and underwent fluorography annually with no pathology. Complaints included prolonged dyspnea on physical exertion and lower limb edema. MSCT showed a picture of left-sided pleural effusion; a blastomatous process was not excluded. Pleural puncture was performed, and 700 ml of sero-hemorrhagic exudate was obtained. The preparation showed abundant cellular composition, with cells predominantly arranged in papillary structures and sheets, nuclei displaced to the periphery, and prominent nucleoli.

Signet Ring Cells in Pleural Effusion: Microscopy

Thu, 19 Feb 2026 08:00:00 +0300

Exudate from a pulmonology patient. Frequently encountered signet ring cells.

🙏 The publication was kindly provided by Ekaterina Nozdrina, Omsk.

Feline Chylothorax: Pleural Effusion Cytology

Mon, 12 Jan 2026 16:00:00 +0300

🔬 VETERINARY CYTOLOGY Cat. Pleural effusion. Chyle. (Left) Macroscopically milky appearance. (Right) Predominance of small lymphocytes with a small number of macrophages containing clear punctate vacuoles. Wright-Giemsa stain.

Adenocarcinoma Signet Ring Cells in Pleural Fluid

Wed, 25 Jun 2025 17:00:00 +0300

🔬 Numerous isolated cells with signet ring deformation, characteristic of adenocarcinoma (Papanicolaou stain), were found in the pleural fluid of a patient with gastric cancer.

👉 Source: Cibas - Cytology. Diagnostic Principles and Clinical Correlates 5 ed (2021)

Pleural Fluid Cytology in Adenocarcinoma Metastasis

Fri, 06 Jun 2025 09:00:01 +0300

🔬 Pleural fluid examination. A 55-year-old male, total right hydrothorax. Presumptive diagnosis: Mts adenocarcinoma.

🙏 This publication was kindly provided by Irina Krainyaya, a clinical laboratory diagnostics physician, Bryansk.

Pleural Fluid Cytology: Identify Cells in Smear

Mon, 02 Jun 2025 10:25:09 +0300

Anonymous question from a subscriber. 📸 Photographs of a pleural fluid smear. Question – what are these cells? Help! 🙏

Patient, 88 years old, cardiology department. Complaints of periodic heart pain. History of IHD, hypertension. What do you think about the cells in the smear? Share your opinion!

Cytological Diagnosis of Malignant Mesothelioma

Wed, 28 May 2025 16:00:01 +0300

Cytology. Malignant Mesothelioma Cells. 🔬 Images 1 and 2: Malignant mesothelioma, unusual variants. In rare cases, mesotheliomas show marked cytoplasmic vacuolization (“clear cell type”). 🔬 Images 3 and 4: Some mesotheliomas consist of small cells; however, the use of the term “small cell mesothelioma” is not recommended to avoid confusion with small cell lung carcinoma.

Sysmex XN Analyzer for Effusion Fluid Analysis

Thu, 15 May 2025 11:00:01 +0300

🧪 Analysis of Body Fluids: Automation vs. Microscope

A study showed that the new hematology analyzer Sysmex XN-2000 performs excellently in counting cells in ascitic and pleural fluid and other biomaterials 🧫. In the absence of tumor cells, the automatic mode yields results comparable to manual counting (up to 96% accuracy 🔬).

Urothelial Carcinoma in Pleural Effusion: Cytology

Tue, 22 Apr 2025 12:00:00 +0300

🔬 Cytology of pleural effusion. The journal Diagnostic Cytopathology described a unique case of urothelial carcinoma detection in pleural effusion. Smears revealed small to medium-sized tumor cells, solitary and in small groups. Their main feature was prominent intracellular vacuoles, which could have been mistaken for macrophages. 📌 Additional tests Immunohistochemical staining showed: ✅ Nuclear expression of GATA3, CK7, and thrombomodulin ❌ Negative reactions for CD68 and CK20 🔴 Oil-Red staining revealed lipids within the vacuoles.

LE Cells in Pleural Fluid in Drug-Induced Lupus

Fri, 14 Mar 2025 16:00:01 +0300

🔬 Cytology. A rare case of LE cells in pleural fluid in a patient with drug-induced lupus.

The article in Diagnostic Cytopathology describes a unique case of lupus erythematosus cells (LE cells) found in the pleural fluid of a 74-year-old patient taking carbamazepine. Lupus erythematosus cells are usually represented by macrophages or neutrophils, but in this case, they were found in eosinophils, which is extremely rare in medical literature.

Diffuse Large B-Cell Lymphoma in Pleural Effusion

Wed, 19 Feb 2025 18:00:00 +0300

🔬 Cytomorphological features of diffuse large B-cell lymphoma (DLBCL) cells in pleural effusion.

Cytoplasmic or nuclear vacuoles and mitoses of DLBCL cells were found in pleural effusions. Wright-Giemsa stain, ×1000). DLBCL cells had cytomorphological features similar to undifferentiated carcinoma or sarcoma.

Pleural Fluid Cytology: Breast Cancer Metastasis

Mon, 10 Feb 2025 11:32:47 +0300

🔬 Cytology. Pleural fluid. From all the material, 1 spherical structure of relatively monomorphic cells was found. Along the periphery, it is visible how the cells close a circle. Such a structure deceptively looks benign and in most cases occurs with metastatic lesions of breast carcinoma.

Differential Diagnosis of Transudates and Exudates

Wed, 08 Jan 2025 17:00:00 +0300

Differential diagnostic signs of exudates and transudates (Kishkun A.A. 2019)

Pleural Effusion Cytology in Metastatic Breast Cancer

Thu, 19 Dec 2024 17:30:00 +0300

🔬 Cytology. Pleural Effusion. Metastatic Breast Cancer.

🙏 Material kindly provided by clinical laboratory diagnostics physician, cytologist Oksana Kadantseva, Yudin City Clinical Hospital, Moscow

Hemophagocytosis in Pleural Fluid: Sediment Microscopy

Wed, 27 Nov 2024 15:00:00 +0300

🔬 The phenomenon of hemophagocytosis in pleural fluid.

🙏 Material kindly provided by KDL intern Nadezhda Petrenko, Blagoveshchensk.

Cholesterol Crystals in Pleural Fluid: Microscopic Analysis

Tue, 26 Nov 2024 15:00:03 +0300

Cholesterol crystals in pleural fluid. Microscopy x200. A 66-year-old male patient from the cardiology department.

🙏 Material kindly provided by biologist of the Clinical Diagnostic Laboratory Tatyana Ivashchenko, Krasnodar.

Adenocarcinoma Metastases in Pleural Fluid

Sat, 16 Nov 2024 09:00:00 +0300

💧Pleural fluid examination in a 79-year-old male. 👉 Diagnosis: Tumor formation in the upper lobe of the right lung.

🔴 Hemorrhagic exudate, protein 27.2 g/l. Color: Hemorrhagic before centrifugation; after centrifugation, the supernatant has a xanthochromic tint.

Hematoidin Crystals in Pleural Fluid Sediment: Clinical Significance

Wed, 16 Oct 2024 15:12:44 +0300

Hematoidin Crystals in Pleural Fluid 🔬

🙏 The clinical case was kindly provided by Vera Kirnas, Biologist, Clinical Diagnostic Laboratory, F.S. Ankudinov Yuzhno-Sakhalinsk City Hospital.

👉 Hematoidin crystals in pleural fluid indicate the long-term presence of blood in the cavity. Hematoidin is a pigment formed from hemoglobin under low oxygen conditions and the absence of active blood cells. The main causes of hematoidin crystals in pleural fluid may include: