Hematology
Neutrophil Hypersegmentation: ICSH Criteria and Causes
ICSH criteria for neutrophil hypersegmentation, causes of morphological changes in vitamin B12, folate deficiency, MDS, and follow-up algorithm.
Tag
Vitamin B12
Hematology
Vitamin B12 Deficiency Anemia and Blue Bone Marrow
A clinical case of severe vitamin B12 deficiency with pancytopenia: blue bone marrow morphology and differential diagnostic errors.
Hematology
Bone Marrow Morphology in Vitamin B12 Deficiency
Bone marrow cell morphology in vitamin B12 deficiency: maturation asynchrony, megaloblastic erythropoiesis, and abnormal mitotic figures.
Hematology
Severe Megaloblastic Anemia: Cellular Morphology
A clinical case of severe megaloblastic anemia, featuring bone marrow morphology with megaloblasts, neutrophil hypersegmentation, and blood parameters.
Hematology
Megaloblastic Anemia: Dyserythropoiesis in Bone Marrow
A clinical case of severe megaloblastic anemia: neurological symptoms, pancytopenia, and morphological signs of dyserythropoiesis in bone marrow smears.
Hematology
Mechanisms of MCV Changes: Microcytosis and Macrocytosis
Diagram of mean corpuscular volume (MCV) changes. Pathogenesis of microcytosis and macrocytosis in iron deficiency, vitamin B12 deficiency, folate deficiency, and liver pathologies.
Hematology
Mitoses in Bone Marrow in B12-Deficiency Anemia
Bone marrow cell morphology in B12-deficiency anemia: smear microscopy, megaloblastic erythropoiesis, and mitotic figures in hematopoietic cells.
Hematology
Differential Diagnosis of Iron Deficiency and B12 Anemia
A clinical case review: differentiating microcytic iron deficiency anemia and vitamin B12 deficiency based on MCV and ferritin levels.
Lab test interpretation
Elevated ALT, AST, and GGT: Differential Diagnosis
Clinical case review: isolated elevation of ALT, AST, and gamma-GT in a 36-year-old woman. Calculation of de Ritis ratio, search for causes, and examination plan.
Hematology
Vitamin B12 Deficiency Anemia: Blood and Bone Marrow
A clinical case of vitamin B12 deficiency anemia: macrocytosis (MCV 118 fL), Howell-Jolly bodies, neutrophil hypersegmentation, and megaloblastic erythropoiesis in the bone marrow.