Human Papillomavirus on Leukoformula

Severe Dyskaryosis in Cervical Cytology with HPV

Fri, 22 May 2026 15:00:00 +0300

Cervical cytology in HPV. The smear shows small, isolated cells with signs of severe dyskaryosis. The cell nuclei are dense, hyperchromatic, with pronounced folding of the contour (“raisin-like”), occupying most of the cell volume. The cytoplasm is scanty and poorly discernible. These cells may be inconspicuous against the background of normal elements, therefore, a thorough examination of the background and the spaces between large squamous cells is required for their detection.

HPV Type 31: Oncogenic Potential and CIN2+ Dysplasia Risk

Sat, 03 Jan 2026 20:00:00 +0300

🔬 Human Papillomavirus Type 31: How dangerous is it for the cervix? A new 10-year study provides the answer.

📌 What was studied? Data from 106,450 women undergoing cervical cancer screening in Turkey (2015–2025) were analyzed. From these, 147 patients with confirmed HPV type 31 infection were identified — one of the high-risk oncogenic strains, in addition to the well-known types 16 and 18.

LSIL and Koilocytic Reaction in Cervical Cytology

Thu, 23 Jan 2025 17:00:00 +0300

🔬 Cervical Cytology. LSIL. Koilocytic Reaction. 🙏 Material kindly provided by clinical laboratory diagnostics physician, cytologist Oksana Kadantseva, Yudin City Clinical Hospital, Moscow

Reference information: ✅ LSIL (low-grade squamous intraepithelial lesion): This is mild dysplasia (CIN 1 by the old classification). It is characterized by changes in cells that are usually caused by active HPV infection. In most cases, LSIL regresses spontaneously, especially in young women with normal immunity. ✅ Koilocytic reaction: This is a specific cellular change observed in HPV infection. Koilocytes are cells with enlarged nuclei, irregular contours, and a clear zone around the nucleus (perinuclear halo). The presence of koilocytes confirms active viral infection.

LSIL Features in Cervical Cytology Smear: A Case Study

Thu, 19 Dec 2024 09:00:00 +0300

🔬 Cervical cytology. A woman of reproductive age, cytological examination during a preventive gynecological check-up, endocervix, LSIL

🙏 Smear photographs and description kindly provided by Kristina Yuryevna, clinical laboratory diagnostics physician, BU “RKB”, Cheboksary

Cervical Cytology: HSIL and Suspected Squamous Cell Carcinoma

Thu, 14 Nov 2024 13:00:01 +0300

🔬 Cervical and endocervical canal cytology. Woman, 29 years old. Last menstruation was 7 days ago. Staining method: Romanowsky. ✅ Cytological conclusion: Against a background of bacterial vaginosis, changes in multilayered squamous epithelial cells were found, including koilocytic atypia. Cells with high-grade intraepithelial neoplasia (HSIL), suspicious for squamous cell carcinoma, were detected. Glandular epithelium with mild atypia is also present. Further examination and specialist consultation are recommended to clarify the diagnosis and choose the optimal management strategy.

Cytology of Moderately Differentiated Cervical Cancer

Tue, 07 May 2024 17:24:00 +0300

🔬Cytology. ✅Moderately differentiated squamous cell carcinoma of the cervix (73-year-old patient). Cellular polymorphism, dyskaryosis, signs of HPV. 👉Material kindly provided by laboratory physician Oksana Vladislavovna Kadantseva. 🎓Find even more useful material on cytology in our LAB-TESTS library.

Morphology of Koilocytes in Cervical Cytology with HPV

Sat, 27 Apr 2024 19:11:57 +0300

🔬Cervical cytology. ✅Koilocytes - squamous epithelial cells in HPV. Large nuclei, degenerative changes, a clear zone around the nuclei, double “kissing” nuclei👩‍❤‍💋‍👨. 🎓Find more cytology material in our library 🧪LAB-TESTS.