
Microscopy Exercise: Cells in a Peripheral Blood Smear
Clinical laboratory diagnostics exercise: identify the cells in a peripheral blood smear next to an apoptotic neutrophil. Microscopy practice.
Topic

Clinical laboratory diagnostics exercise: identify the cells in a peripheral blood smear next to an apoptotic neutrophil. Microscopy practice.

We examine the morphology of a cell with a heart-shaped nucleus in a microphotograph. We discuss possible causes of this nuclear shape and its diagnostic significance in hematology.

A clinical case of autoimmune hemolytic anemia featuring massive normoblastosis, elevated WBC on hematology analyzer, and leukocyte recalculation.

Clinical case of mechanical hemolysis after heart valve replacement: appearance of schistocytes in blood smear with paravalvular leak and diagnosis.

Morphological features of the granulocytic series: from blast and promyelocyte to mature segmented neutrophil in a blood smear under the microscope.

A case of severe platelet dysplasia in a 66-year-old patient. Morphology of atypical platelets in blood smear, analyzer histograms, and resemblance to trypanosomiasis.

A clinical case of cytological examination of a cervical smear from a 46-year-old woman diagnosed with HSIL, with suspicion of squamous cell carcinoma (SCC).

A case of severe poikilocytosis in an ICU patient: schistocytes, normoblasts, and erythrocyte fragmentation (dumbbell and rod shapes) in a blood smear.

Morphological features of nucleated erythroid cells: an example of a normoblast with a lobulated nucleus in a digital blood smear with signs of dyserythropoiesis.

Holes and ring-shaped nuclei in leukocytes: morphological features of reactive lymphocytes in EBV, granulocyte dysplasia, and differential diagnostics.

Learn about Cabot rings in erythrocytes: their nature, diagnostic significance in megaloblastic anemia, and erythropoiesis disorders. Cytology of blood smears.

Explore the morphological features of peripheral blood basophils in ferrets, dogs, and cats. Microscopy of blood smears stained with Romanowsky-Giemsa at 1000x magnification.