
Unusual Inclusions in Lymphocytes: A Microscopy Challenge
Lymphocytes with large atypical inclusions were found in an animal's peripheral blood smear. Determine the nature of the granulation in the cell cytoplasm.
Topic

Lymphocytes with large atypical inclusions were found in an animal's peripheral blood smear. Determine the nature of the granulation in the cell cytoplasm.

Blood smear morphology in Mycoplasma pneumoniae: severe cold agglutination of red blood cells, falsely elevated MCHC, and reactive lymphocytes with uropods.

Bone marrow morphology in parvovirus B19 infection: characteristics of giant proerythroblasts, erythropoiesis features, and laboratory diagnostics.

Morphological features of bone marrow in Pompe disease: pronounced vacuolization of plasma cells, PAS cytochemistry, and acid phosphatase reaction.

Cytological features of granulomatous inflammation in a lymph node: epithelioid histiocytes and lymphocytes in a fine needle aspirate smear, Diff-Quik stain.

Cytological signs of silicone lymphadenitis: accumulation of macrophages with numerous optically empty vacuoles in a lymph node aspirate.

A practical exercise in leukocyte morphology: identify which numbered cell in the peripheral blood smear is not a reactive lymphocyte.

Morphological features of May-Hegglin anomaly in a child's blood smear: giant platelets and Döhle body-like inclusions in neutrophil cytoplasm.

An interactive exercise on blood cell morphology: determine the number of nucleated erythrocyte precursors (erythroblasts) in the provided gallery.

Morphology of a large granular lymphocyte in mycoplasma infection: cytotoxic granules moving into a cytoplasmic protrusion in a blood smear.

Key criteria for describing cell morphology: assessing size, nucleo-cytoplasmic ratio, cytoplasm structure, nuclei, chromatin, and nucleoli.

Morphology of Heinz bodies in erythrocytes with supravital Nile blue sulfate staining. Causes of formation: enzymopathies and unstable hemoglobin.