
Erythrocyte Morphology in Thalassemia and Hemoglobinopathies
Peripheral blood smears in beta-thalassemia, sickle cell anemia, and hemoglobinopathies C and E: HbC crystals, sickle and target cells.
Topic

Peripheral blood smears in beta-thalassemia, sickle cell anemia, and hemoglobinopathies C and E: HbC crystals, sickle and target cells.

Morphological criteria for differentiating monocytes and lymphocytes in a peripheral blood smear: nuclear features, chromatin structure, and cytoplasmic properties.

Emperipolesis in bone marrow smear: intact cell penetration into megakaryocyte cytoplasm. Morphology and clinical significance of the finding.

Explore the morphological features of proplatelets under smear microscopy. Learn about megakaryocyte extensions and the process of blood platelet formation.

Morphology of erythroblastic islands in bone marrow smears: structure of erythroid rosettes around a macrophage, differentiation of erythroid cells.

A clinical case of congenital sideroblastic anemia with HSPA9 mutation: blood picture, dyserythropoiesis, and ring sideroblasts in bone marrow.

A clinical case of pertussis in a 2-year-old child: pronounced lymphocytosis, lymphocytes with cleaved nuclei, and smudge cells in the blood smear.

A clinical case of infectious mononucleosis in a 7-year-old child: complete blood count parameters and morphology of reactive lymphocytes in a blood smear.

Analysis of a child's complete blood count: moderate absolute neutropenia and hypereosinophilia, mistakenly considered normal for age by doctors.

Laboratory hematology test: select the conditions in which a large number of Howell-Jolly bodies are found in a peripheral blood smear.

How endothelial cells of blood vessels appear in bone marrow aspirate smears: morphological features and differential diagnosis.

How iron deficiency anemia was described in the 16th century: chlorosis, maiden's disease, and the first clinical observations by German physician Johannes Lange.