Hematology
Proerythroblast vs. Plasma Cell: Morphological Distinctions
Key criteria for differential diagnosis of proerythroblasts and plasma cells: nuclear location, cytoplasmic basophilia, and N:C ratio.
Topic
Hematology
Hematology
Platelet Formation and Fate of Mature Megakaryocyte Nucleus
How blood platelets are formed: a diagram of megakaryocyte cytoplasm fragmentation and phagocytosis of its residual nucleus by bone marrow macrophages.
Hematology
Bone Marrow as a Hematopoietic Organ: History of Discovery
Explore the history of hematopoiesis: Ernst Neumann's 1868 discovery of bone marrow's role and Mikhail Arinkin's 1928 introduction of in vivo bone marrow puncture.
Hematology
Pinocchio Cells in Blood Smear: Lymphocyte Morphology
Morphological features of Pinocchio cells in blood smears during interleukin-2 therapy. Immunophenotype and cytochemical markers of activated T-lymphocytes.
Hematology
Myelogram Indicators in Hematological Diseases
Comparative table of myelogram changes in anemias, infections, leukemias, and agranulocytosis, contrasted with normal bone marrow indicators.
Hematology
Hair Loss and IDA Risk: Which Test to Order?
Clinical case: a patient complains of hair loss with normal hemoglobin. Which lab test should be ordered to assess iron metabolism?
Hematology
Evaluation of a Diagnostic Algorithm for Macrocytic Anemia
An analysis of a proposed diagnostic scheme for macrocytic anemia: sternal puncture, assessment of vitamin B12, folate, reticulocyte, and platelet levels.
Hematology
Hematology Exercise: Cell Identification in Blood Smear
A practical laboratory hematology exercise: evaluating cell morphology in a blood smear. Test your skills in differential diagnosis of precursors.
Hematology
Blood Group Determination on the Shroud of Turin
Laboratory findings on blood traces from the Shroud of Turin: hemoglobin detection, determination of blood group AB (IV), and DNA analysis.
Hematology
Drug-Induced Immune Hemolytic Anemia: Medications
A table of medications causing immune hemolytic anemia and the importance of collecting a pharmacological history when the direct Coombs test is positive.
Hematology
Counting Band Neutrophils in Blood Smears: Why It Matters
Why determine band neutrophils in the leukocyte formula: diagnosis of sepsis and SIRS, the link between band shift and mortality risk.
Hematology
Neutrophil Phagocytosis of Bacteria in Bacteremia
A clinical case of bacteremia: detection of rod-shaped bacteria phagocytosed by neutrophils during digital microscopy of a peripheral blood smear.